tert-Butyl (E)-7-[3′-(4”-fluorophenyl)-1′-methylethyl-indol-2′-yl]-3-hydroxy-5-oxo-6-heptenoate is a chiral hydroxy keto ester that appears as a white to off-white powder. It is a key advanced intermediate in the synthesis of fluvastatin, an HMG-CoA reductase inhibitor used for hypercholesterolaemia.
tert-Butyl (E)-7-[3′-(4”-fluorophenyl)-1′-methylethyl-indol-2′-yl]-3-hydroxy-5-oxo-6-heptenoate
Category:Organic Intermediates
CAS No.:375846-25-6
Product Grade: Pharmaceutical Grade
Purity / Assay: 98%
Molecular Formula:C₂₈H₃₂FNO₄
Molecular Weight:465.56
EINECS No.:609-442-4
Synonym(s):Fluvastatin intermediate; tert-Butyl (E)-7-[3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl]-5-hydroxy-3-oxohept-6-enoate
tert-Butyl (E)-7-[3′-(4”-fluorophenyl)-1′-methylethyl-indol-2′-yl]-3-hydroxy-5-oxo-6-heptenoate is a chiral hydroxy keto ester that appears as a white to off-white powder. It is a key advanced intermediate in the synthesis of fluvastatin, an HMG-CoA reductase inhibitor used for hypercholesterolaemia.
1. Key intermediate for fluvastatin API manufacturing.
2. Chiral building block for statin and cardiovascular drug synthesis.
3. Precursor for functionalized indole derivatives.
4. Reagent in asymmetric synthesis and chiral resolution.
25kg/bag; 25kg/drum
CAS No.: 375846-25-6
Product Name: tert-Butyl (E)-7-[3′-(4”-fluorophenyl)-1′-methylethyl-indol-2′-yl]-3-hydroxy-5-oxo-6-heptenoate
Purity / Assay:98%
Molecular Formula:C₂₈H₃₂FNO₄
Molecular Weight:465.56
EINECS No.:609-442-4
Synonym(s):Fluvastatin intermediate; tert-Butyl (E)-7-[3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl]-5-hydroxy-3-oxohept-6-enoate
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