Daptomycin
Daptomycin (CAS:103060-53-3) is a cyclic lipopeptide antibiotic with rapid, concentration-dependent bactericidal activity against Gram-positive pathogens. It disrupts bacterial membrane potential and function in a calcium-dependent manner, offering a valuable option for serious infections including MRSA and vancomycin-resistant enterococci, and is supplied as pharma-grade powder for injectable drug manufacturing. With its Pharma Grade designation, every lot carries a complete certificate of analysis including assay, purity and physical data, giving QC teams everything needed for release testing. The product is backed by flexible 25kg/drum, 5kg/bag packaging, steady stock availability and export documentation, so customers can plan procurement with confidence and keep production running without interruption.
KieRay Chem is recognized as a reliable partner for Daptomycin (CAS:103060-53-3), with dedicated production capacity, strict process control and a proven global track record. Batch-to-batch reproducibility is guaranteed by standardized production and full QC release, with COA, technical datasheets and safety files delivered with every order. Customized grades, pack sizes and dependable delivery schedules help customers maintain uninterrupted production and end-product quality worldwide. With a strong export record and customer-first service, KieRay Chem ensures every tonne of product meets the highest standards of purity and safety.
## Daptomycin (CAS 103060-53-3): Key Functions and Uses
1. **Cyclic Lipopeptide Antibiotic**
Daptomycin is a calcium-dependent cyclic lipopeptide antibiotic used against serious infections caused by susceptible **Gram-positive bacteria**. It is particularly important in hospital and infectious-disease settings where resistant bacterial pathogens may be involved.
2. **Treatment of Complicated Skin Infections**
Approved injectable formulations are used to treat complicated skin and skin-structure infections caused by susceptible organisms, including certain *Staphylococcus aureus*, *Streptococcus*, and *Enterococcus* species, according to local product labeling.
3. **Staphylococcus aureus Bloodstream Infections**
Daptomycin is used for selected *Staphylococcus aureus* bloodstream infections, including bacteremia. In approved indications, it may also be used for associated right-sided infective endocarditis under qualified medical supervision.
4. **Activity Against Resistant Gram-Positive Pathogens**
Daptomycin is valued in antimicrobial treatment strategies involving difficult-to-treat Gram-positive bacteria, including some methicillin-resistant *Staphylococcus aureus* (MRSA) and vancomycin-resistant *Enterococcus faecium* (VRE) infections. Susceptibility testing and infectious-disease expertise are essential.
5. **Calcium-Dependent Membrane Mechanism**
The drug binds to bacterial membranes in a calcium-dependent manner and disrupts membrane function, including membrane potential and ion balance. This rapid membrane-active mechanism ultimately inhibits essential bacterial processes and leads to cell death.
6. **Research and Antimicrobial Development**
CAS 103060-53-3 is used in microbiology, pharmaceutical research, antibacterial screening, pharmacology, resistance surveillance, susceptibility testing, and studies of bacterial membrane biology and antibiotic mechanisms.
7. **Quality and Procurement Considerations**
When sourcing Daptomycin, buyers should verify identity, purity, potency, sterility or non-sterile status, formulation, endotoxin specifications where relevant, certificate of analysis, storage conditions, and regulatory documentation. Useful SEO keywords include **Daptomycin, CAS 103060-53-3, cyclic lipopeptide antibiotic, Gram-positive antibacterial, MRSA research, bacteremia treatment, infective endocarditis, and antimicrobial research compound**.
8. **Important Medical and Safety Notice**
Daptomycin is a prescription antibacterial medicine and must be administered according to an authorized product label and professional medical guidance. Treatment may require monitoring for muscle-related toxicity, creatine phosphokinase changes, renal considerations, and drug interactions. Research-grade Daptomycin is for laboratory use only and is not intended for self-medication or unauthorized therapeutic application.
Product Name: Daptomycin
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