Staurosporine
Staurosporine (CAS:62996-74-1) is a potent, broad-spectrum inhibitor of protein kinases, originally isolated from Streptomyces staurosporeus. It binds competitively to the ATP pocket of many kinases and is an essential tool in cell signaling research, oncology drug discovery and apoptosis studies, supplied as high-purity powder for research and pharmaceutical use. Quality is locked down at every stage: production follows standardized parameters, and each Pharma Grade batch is sampled and tested before release, with records available for customer audit. Purchasers gain real supply security, because 5kg/bag, 25kg/drum options, short lead times and responsive technical support allow seamless qualification into existing formulations or production lines.
As a professional fine-chemical manufacturer and exporter, KieRay Chem delivers Staurosporine (CAS:62996-74-1) with dependable consistency and full supply-chain transparency. Each shipment is released only after passing comprehensive QC covering assay, impurity profile and physical parameters, accompanied by COA, TDS and SDS documentation. Flexible packaging, reliable sea and air logistics, and a professional technical team make KieRay Chem the effortless choice for both R&D quantities and bulk supply. From initial samples to industrial-scale volumes, KieRay Chem provides the stability, documentation and service excellence that demanding buyers rely on.
1. **Staurosporine (CAS 62996-74-1) for Protein Kinase Research**
Staurosporine is a well-known, broad-spectrum protein kinase inhibitor widely used in biochemical and cell-based research. By interacting with the ATP-binding sites of various kinases, it supports studies of kinase signaling, phosphorylation pathways, and cellular regulation. Its established research history makes Staurosporine a valuable reference compound for laboratories investigating signal transduction and enzyme activity.
2. **Apoptosis and Cell Death Studies**
Staurosporine is frequently used to induce apoptosis in cultured cells, helping researchers examine caspase activation, mitochondrial changes, DNA fragmentation, and other programmed cell death mechanisms. As a laboratory reagent, it can serve as a positive control when evaluating apoptosis-related assays, cytotoxicity models, and anticancer drug responses.
3. **Cell Cycle, Differentiation, and Signaling Applications**
Researchers use Staurosporine to explore cell-cycle arrest, cellular differentiation, proliferation control, and kinase-dependent signaling networks. Its ability to affect multiple kinase pathways makes it suitable for pathway validation, mechanism-of-action studies, and comparative evaluation of selective kinase inhibitors in cancer biology and molecular pharmacology.
4. **Reliable Research Reagent for Assay Development**
Staurosporine is easy to identify when sourcing materials for laboratory experiments. It is commonly incorporated into Western blotting, flow cytometry, fluorescence, viability, apoptosis, and high-content screening workflows. Researchers should optimize concentration, exposure time, cell type, and solvent conditions because biological responses may vary across experimental systems.
5. **Why Choose Staurosporine 62996-74-1?**
Staurosporine offers broad research utility, strong literature recognition, and practical value for kinase and apoptosis experiments. It is intended for professional research use only and is not a diagnostic, therapeutic, food, or household product. For dependable results, select a supplier providing clear product specifications, verified purity, batch documentation, storage guidance, and technical support.
Product Name: Staurosporine
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