2,5-bisbenzoic Acid
2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid (CAS 35480-52-5) is a fluorinated aromatic carboxylic acid derivative characterized by two trifluoroethoxy side chains attached to a central benzene ring core. The presence of multiple strong carbon-fluorine bonds imparts exceptional thermal stability, lipophilicity, and unique electronic properties to the chemical architecture. This solid crystalline material serves as an indispensable organic synthesis intermediate, particularly in fine chemical manufacturing and pharmaceutical development. The fluorinated ether substituents significantly alter the metabolic stability and receptor-binding affinity of target molecules derived from this scaffold. Due to its precise structural features and high purity, it is widely utilized by synthetic chemists to construct complex bio-active molecules, agrochemical agents, and specialized functional materials requiring high fluorine content and chemical resilience.
– Pharmaceutical Intermediate: Primary chemical precursor utilized in the multi-step synthesis of cardiovascular and antiarrhythmic active pharmaceutical ingredients, most notably flecainide acetate.
– Fluorinated Chemical Synthesis: Applied as a fluorinated building block in fine chemical manufacturing to introduce stable bis(trifluoroethoxy) aromatic groups into complex organic molecules.
– Medicinal Chemistry Research: Extensively employed in drug discovery programs to tune lipophilicity, metabolic resistance, and pharmacological profiles of novel therapeutic candidates.
Product Name: 2,5-bisbenzoic Acid
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