Desulfovardenafil
Desulfovardenafil (CAS: 224789-21-3) is a key synthetic intermediate in the production of vardenafil, a potent phosphodiesterase type 5 (PDE5) inhibitor used in the treatment of erectile dysfunction. Structurally, this compound represents the core imidazotriazinone scaffold of vardenafil prior to sulfonylation, featuring the characteristic 2-ethoxy-5-methyl-7-propyl substitution pattern on the fused heterocyclic system. As a regulated pharmaceutical intermediate, it is manufactured under stringent quality controls to ensure high chemical purity and consistency for downstream processing. The compound is primarily of interest to licensed pharmaceutical manufacturers engaged in the multi-step synthesis of vardenafil hydrochloride. Proper documentation, secure handling, and compliance with regulatory requirements are essential throughout procurement and processing. This intermediate exemplifies the specialized building blocks required in modern synthetic drug manufacturing.
– PDE5 Inhibitor Synthesis: Serves as the key core intermediate in the multi-step manufacture of vardenafil for pharmaceutical applications.
– API Process Development: Used by licensed manufacturers in process optimization, scale-up, and validation of vardenafil production routes.
– Analytical Reference: Employed as a reference standard and process intermediate in quality control and impurity profiling of vardenafil products.
Product Name: Desulfovardenafil
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