2-[2-phenoxy]ethyl Methanesulfonate
2-[2-phenoxy]ethyl Methanesulfonate (CAS: 160969-03-9) is a functionalized alkyl methanesulfonate (mesylate) ester featuring a phenoxy-substituted ethyl chain. As an activated alcohol derivative, the mesylate group serves as an excellent leaving group in nucleophilic substitution reactions, enabling efficient carbon-heteroatom bond formation in pharmaceutical and fine chemical synthesis. The phenoxy aromatic ring provides a hydrophobic handle that can be further functionalized or contributes to the pharmacological properties of derived molecules. This compound is typically employed as a key alkylating intermediate in the construction of ether linkages, amine alkylation products, and carbon-chain extensions during multi-step API synthesis. Supplied as a high-purity crystalline solid, it ensures consistent reactivity and predictable performance in downstream transformations. Proper storage under dry, cool conditions preserves its stability for synthetic applications.
– Pharmaceutical Alkylation: Used as an activated alkylating agent for introducing 2-phenoxyethyl groups into drug candidates during API synthesis.
– Ether and Amine Synthesis: Serves as a mesylate leaving-group intermediate for efficient O- and N-alkylation reactions in multi-step synthesis.
– Fine Chemical Manufacturing: Applied in the production of specialty intermediates requiring phenoxy-terminated carbon chains for fragrance and material applications.
– Medicinal Chemistry Research: Employed in drug discovery programs for structure-activity relationship studies involving phenoxyalkyl substitution.
Product Name: 2-[2-phenoxy]ethyl Methanesulfonate
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