L-Citrulline
L-Citrulline, identified by CAS number 372-75-8, is a naturally occurring alpha-amino acid that plays a critical role as an intermediate in the urea cycle. Chemically known as (2S)-2-amino-5-(carbamoylamino)pentanoic acid, it is characterized by its white crystalline appearance and high solubility in water. Unlike many other amino acids, it is not coded for by DNA but is produced through the enzymatic modification of arginine or as a byproduct of nitric oxide synthesis.
In industrial and laboratory settings, L-Citrulline is valued for its high purity and stability under standard storage conditions. As a vital component in nitrogen metabolism, it serves as a precursor to L-arginine, facilitating the efficient removal of ammonia from biological systems. Its chemical structure makes it a versatile building block in organic synthesis and a key subject in metabolic research, particularly concerning amino acid transport and enzymatic pathways.
• In the nutritional and dietary supplement industry, L-Citrulline is widely utilized as a primary ingredient in formulations designed to support metabolic health and nitrogen balance. It is often preferred over direct arginine supplementation due to its superior bioavailability and its role in increasing plasma arginine levels, which assists in the endogenous production of nitric oxide and the management of metabolic waste products.
• Within the field of biochemical research, this compound serves as a fundamental reagent for studying the urea cycle and nitrogenous waste excretion. Researchers employ L-Citrulline to investigate enzymatic activities, such as those involving nitric oxide synthase and peptidylarginine deiminase, providing insights into protein post-translational modifications and various physiological signaling pathways.
• The pharmaceutical and chemical synthesis sectors utilize L-Citrulline as a chiral building block for the development of complex molecules and active pharmaceutical ingredients. Its unique carbamoyl side chain allows for specific chemical transformations, making it useful in the synthesis of specialized peptides and other nitrogen-containing organic compounds required for advanced therapeutic applications.
Product Name: L-Citrulline
For global customers, we provide complete technical documentation to support product evaluation, regulatory compliance and safe handling during transportation and application.