Atorvastatin Intermediate M4
Atorvastatin Intermediate M4 (CAS: 125971-96-2) is a white to off-white crystalline diketo-amide compound used as a key building block in atorvastatin synthesis. It is the elaborated 1,4-diketone that serves as the parent nucleus of the atorvastatin molecule, undergoing Paal-Knorr condensation with the chiral side-chain amine to construct the drug’s pyrrole core. This makes it central to the production of the world’s most widely used cholesterol-lowering medicine. The intermediate is manufactured and traded against tight impurity specifications, since downstream condensation and purification steps depend on its quality. It is supplied as a free-flowing powder suitable for standard charging and drying operations. Customers procure it for generic atorvastatin calcium API manufacture at industrial scale, where consistency and documentation are essential.
• Statin API synthesis: a core diketo-amide intermediate for atorvastatin calcium, the active ingredient in leading cholesterol drugs.
• Chiral building block: undergoes stereoselective transformation to install the 3,5-dihydroxy acid side chain of the final API.
• Quality-critical supply: produced against tight impurity limits including des-fluoro and total impurity specifications.
• Industrial scale: traded in drums and bulk for generic statin manufacturers with established global demand.
Product Name: Atorvastatin Intermediate M4
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