tert-Butyl (4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxane-4-acetate
tert-Butyl (4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxane-4-acetate (CAS: 124752-23-4) is a chiral, protected hydroxy-oxo ester used as a pharmaceutical synthesis building block. Its dioxane framework carries a formyl group and tert-butyl acetate side chain, providing defined stereochemistry and functional handles for further transformations. Patent literature identifies it as a key intermediate for preparing several statin medicines. Supplied as a solid for synthesis, analytical, and research work, it is not intended for direct human use. Commercial listings recommend cold storage, including inert storage below -20°C in one listing.
• Used as a chiral synthetic intermediate in routes to statins, including atorvastatin, cerivastatin, fluvastatin, pitavastatin, and rosuvastatin.
• Functions as a protected chiral building block; its aldehyde enables further transformations, while its ester and acetal groups support controlled downstream synthesis.
• Applied in pharmaceutical research and development, including intermediate synthesis development and analytical studies.
• Supplied by reference-standard vendors for analytical testing, method development and validation, quality control, impurity profiling, and compound identification or quantification.
Product Name: tert-Butyl (4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxane-4-acetate
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