Dibutyl Squarate
Dibutyl squarate is a dialkyl ester of squaric acid, a strained four-membered cyclobutenedione system. The electron-deficient ring undergoes facile substitution with amines and other nucleophiles, making it a versatile electrophilic building block for pharmaceuticals, dyes, and bioconjugation chemistry.
Pharmaceutical intermediates: used in the synthesis of APIs and bioactive squaramide derivatives; Bioconjugation and labelling: reacts with amines to attach squarate tags to proteins and peptides; Dye and materials chemistry: a building block for functional dyes and electron-deficient aromatic systems; Research applications: employed in squaric acid chemistry for ligand and sensor development.
Product Name: Dibutyl Squarate
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