This compound (CAS 1132832-75-7), also known as KG-1, is a brominated and fluorinated diaryl methanone bearing a thiophene ring. It is a highly selective pharmaceutical intermediate specifically designed for the preparation of canagliflozin, a sodium-dependent glucose co-transporter 2 (SGLT2) inhibitor used in type 2 diabetes treatment.
5-Bromo-2-methylphenyl 5-(4-fluorophenyl)-2-thienyl methanone
Category:Organic Intermediates
CAS No.:1132832-75-7
Product Grade: Industrial Grade
Purity / Assay: 98%
Molecular Formula:C₁₈H₁₂BrFOS
Molecular Weight:375.25
Synonym(s):(5-Bromo-2-methylphenyl)(5-(4-fluorophenyl)thiophen-2-yl)methanone; KG-1
This compound (CAS 1132832-75-7), also known as KG-1, is a brominated and fluorinated diaryl methanone bearing a thiophene ring. It is a highly selective pharmaceutical intermediate specifically designed for the preparation of canagliflozin, a sodium-dependent glucose co-transporter 2 (SGLT2) inhibitor used in type 2 diabetes treatment.
1. Critical intermediate in the synthesis of canagliflozin, an SGLT2 inhibitor for type 2 diabetes management.
2. Building block for other SGLT2 inhibitor drug candidates in medicinal chemistry programs.
3. Synthetic intermediate for functionalized thiophene-containing pharmaceutical compounds.
4. Potential substrate for aryl carbon–halogen bond functionalization in organic synthesis.
25kg/drum; 25kg/bag
CAS No.: 1132832-75-7
Product Name: 5-Bromo-2-methylphenyl 5-(4-fluorophenyl)-2-thienyl methanone
Purity / Assay:98%
Molecular Formula:C₁₈H₁₂BrFOS
Molecular Weight:375.25
Synonym(s):(5-Bromo-2-methylphenyl)(5-(4-fluorophenyl)thiophen-2-yl)methanone; KG-1
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