1–2-ethoxybenzene
1–2-ethoxybenzene (CAS: 3259-03-8) is a brominated aromatic ether intermediate featuring a reactive bromine substituent alongside an ethoxy group on a substituted benzene ring. The bromine atom serves as a versatile handle for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, and Buchwald-Hartwig amination, while the ether functionality modulates electronic properties and solubility of derived products. This building block is employed in pharmaceutical synthesis for constructing complex aromatic frameworks, in agrochemical manufacturing for active ingredient elaboration, and in materials science for preparing liquid crystal and OLED intermediates. Its well-defined substitution pattern enables regioselective transformations with predictable outcomes. Supplied as a high-purity liquid or solid, it supports reproducible multi-step synthetic programs. Proper storage away from light and moisture maintains its reactivity for demanding coupling applications.
– Cross-Coupling Chemistry: Used as a brominated building block in Suzuki, Heck, and amination reactions for pharmaceutical and agrochemical synthesis.
– Pharmaceutical Intermediate: Serves as a scaffold for constructing substituted aromatic drug candidates and active ingredient frameworks.
– Materials Science: Applied in the synthesis of liquid crystal, OLED, and specialty aromatic compounds for electronics applications.
– Agrochemical Synthesis: Employed in building crop protection molecules requiring defined aromatic substitution patterns.
Product Name: 1–2-ethoxybenzene
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