2–1,1-dimethoxyethane
2–1,1-dimethoxyethane (CAS: 1228258-40-9) is a functionalized amino acetal featuring a protected carbonyl group and a primary amine on a compact two-carbon framework. The dimethyl acetal masks an aldehyde functionality that can be revealed under mild acidic conditions, while the free primary amine enables amide formation, reductive amination, and nucleophilic reactions. This dual-reactivity building block is valuable in pharmaceutical synthesis for constructing heterocycles, peptide-like structures, and multifunctional intermediates where orthogonal protection and reactivity are required. It also serves in agrochemical and specialty chemical synthesis for introducing aminoacetaldehyde equivalents into target molecules. The compound’s defined stereochemistry and high purity support predictable outcomes in multi-step synthetic programs. Proper storage under neutral, anhydrous conditions preserves both the amine and acetal functionalities for demanding transformations.
– Aldehyde Equivalent Chemistry: Used as a protected aminoacetaldehyde building block enabling controlled carbonyl reactions after mild acid deprotection.
– Heterocycle Synthesis: Serves in constructing imidazoles, pyrroles, and other nitrogen heterocycles through amine and aldehyde bifunctional reactivity.
– Pharmaceutical Intermediate: Applied in synthesizing amino acid derivatives, peptidomimetics, and multifunctional drug candidates.
– Agrochemical Building Block: Employed in preparing nitrogen-containing intermediates for crop protection chemistry.
Product Name: 2–1,1-dimethoxyethane
For global customers, we provide complete technical documentation to support product evaluation, regulatory compliance and safe handling during transportation and application.