2-Bromodibenzofuran
2-Bromodibenzofuran (CAS:86-76-0) is a brominated dibenzofuran derivative that serves as a versatile aryl bromide coupling partner in organic synthesis. Its bromine handle enables Suzuki, Stille and Buchwald-Hartwig reactions to construct extended conjugated systems for pharmaceuticals, agrochemicals and organic optoelectronic materials. The compound is supplied as a stable white crystalline powder with high GC purity for reproducible transformation. The Reagent Grade specification is maintained by disciplined manufacturing and full analytical release, with COA, technical and safety documentation accompanying each order. Combined with 25kg/drum, 25kg/bag packaging options and dependable worldwide delivery, this quality system gives formulators and distributors a low-risk, high-continuity source they can qualify once and rely on for years.
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## 2-Bromodibenzofuran (CAS 86-76-0): Key Functions and Uses
1. **Brominated Dibenzofuran Building Block**
2-Bromodibenzofuran is a brominated polycyclic aromatic compound used mainly as a specialized intermediate in organic synthesis, medicinal chemistry, and advanced materials research. Its defined bromine position enables further molecular functionalization.
2. **Intermediate for Organic Synthesis**
The compound can be used to prepare substituted dibenzofuran derivatives and other complex aromatic structures. Its rigid dibenzofuran framework is useful for designing molecules with tailored electronic, optical, and steric properties.
3. **Cross-Coupling and C–C Bond Formation Research**
The aryl bromide group provides a reactive site for palladium-catalyzed and other transition-metal-mediated coupling reactions. Researchers may use it in Suzuki, Stille, Buchwald–Hartwig, and related transformations to connect the dibenzofuran unit with aryl, heteroaryl, alkynyl, or amino fragments.
4. **Pharmaceutical and Fine-Chemical Intermediate**
CAS 86-76-0 may support the synthesis of pharmaceutical candidates, bioactive molecules, and fine-chemical intermediates containing dibenzofuran or fused aromatic motifs. It is useful in route development, compound-library synthesis, and structure–activity relationship studies.
5. **Friedel–Crafts Acylation Research**
2-Bromodibenzofuran can be used as a reagent or substrate in selected Friedel–Crafts acylation reactions. This enables the preparation of acylated dibenzofuran derivatives for subsequent synthetic and materials applications.
6. **OLED and Organic Electronic Materials Research**
Dibenzofuran-based structures are relevant to organic optoelectronic materials, OLED intermediates, organic semiconductors, and functional thin films. 2-Bromodibenzofuran can serve as a precursor for constructing larger conjugated molecules with designed energy levels and photophysical properties.
7. **Analytical and Process-Development Applications**
Researchers can use this compound in reaction screening, process optimization, impurity studies, HPLC, GC, LC–MS, and NMR characterization. Buyers should confirm purity, positional isomer identity, residual solvents, and certificate-of-analysis data.
8. **Quality, Procurement, and Safety Considerations**
When sourcing 2-Bromodibenzofuran 86-76-0, buyers should verify chemical identity, assay, melting range, particle or solid form, packaging, storage requirements, and technical documentation. Useful SEO keywords include **2-Bromodibenzofuran, 2-Bromodibenzo[b,d]furan, CAS 86-76-0, aryl bromide, dibenzofuran intermediate, Suzuki coupling substrate, pharmaceutical intermediate, OLED material precursor, and organic synthesis reagent**. This product is intended for qualified research and industrial development; users should follow the supplier’s Safety Data Sheet and validated laboratory procedures.
Product Name: 2-Bromodibenzofuran
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