2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one (CAS 1013916-37-4) is a heterocyclic intermediate used in the synthesis of palbociclib, a CDK4/6 inhibitor for breast cancer. It is a key building block for pyrido-pyrimidine derivatives and is handled as a white to off-white powder under pharmaceutical-grade conditions.
2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one
Category:Organic Intermediates
CAS No.:1013916-37-4
Product Grade: Pharma grade
Purity / Assay: 97%
Molecular Formula:C₁₃H₁₄ClN₃O
Molecular Weight:263.73
EINECS No.:800-066-8
Synonym(s):2-Chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one; Palbociclib intermediate
2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one (CAS 1013916-37-4) is a heterocyclic intermediate used in the synthesis of palbociclib, a CDK4/6 inhibitor for breast cancer. It is a key building block for pyrido-pyrimidine derivatives and is handled as a white to off-white powder under pharmaceutical-grade conditions.
1. Key intermediate for palbociclib and CDK4/6 inhibitor synthesis. 2. Building block for pyrido[2,3-d]pyrimidine derivatives. 3. Anticancer pharmaceutical process development. 4. Reference compound for kinase-inhibitor research.
25kg/drum; 200kg/drum
CAS No.: 1013916-37-4
Product Name: 2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one
Purity / Assay:97%
Molecular Formula:C₁₃H₁₄ClN₃O
Molecular Weight:263.73
EINECS No.:800-066-8
Synonym(s):2-Chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one; Palbociclib intermediate
For global customers, we provide complete technical documentation to support product evaluation, regulatory compliance and safe handling during transportation and application.