2,6-Difluorobenzamide
2,6-Difluorobenzamide (CAS: 18063-03-1) is a white crystalline aromatic amide bearing two fluorine atoms flanking the amide group. It is a valuable intermediate in the synthesis of pharmaceuticals and agrochemicals, including benzoylurea insect growth regulators that act on chitin synthesis in insect pests. The difluorinated ring improves lipophilicity and metabolic stability in target molecules, making it a preferred building block for modern crop-protection chemicals. The amide function can be dehydrated to the nitrile or acylated for further elaboration, supporting flexible synthetic routes. Customers use it for acylation, dehydration, and further ring-functionalization chemistry in the production of fluorinated fine chemicals.
• Agrochemicals: a key intermediate for benzoylurea insecticides that inhibit chitin synthesis and control Lepidoptera and other pests.
• Pharmaceutical synthesis: used to prepare fluorinated aromatic drug intermediates with improved binding and metabolic stability.
• Fluoroaromatic building block: supports further functionalization of the difluorinated phenyl core in discovery and process programs.
• Fine chemicals: applied in specialty amide and nitrile chemistry for advanced materials and research products.
Product Name: 2,6-Difluorobenzamide
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