4-Chlorobutyryl Chloride
4-Chlorobutyryl Chloride (CAS: 4635-59-0) is a difunctional acid chloride supplied as a colourless to light yellow clear liquid with a sharp, irritating odour.
The molecule contains both an acyl chloride and a terminal alkyl chloride, so it can be used for successive acylation and substitution steps, cyclisation to cyclopropane or butyrolactone systems, and introduction of a four-carbon chain bearing a leaving group.
• Pharmaceutical intermediates: a four-carbon acylating agent for building piperidinone, pyrrolidinone and cyclopropylamine frameworks.
• Agrochemical synthesis: used in the preparation of herbicidal and fungicidal actives bearing a chloropropyl chain.
• Cyclisation chemistry: cyclises to gamma-butyrolactone and cyclopropane derivatives under basic conditions.
• Polymer modification: introduces reactive acid chloride functionality onto hydroxyl- or amine-containing polymers.
Product Name: 4-Chlorobutyryl Chloride
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