This compound is a quinazoline intermediate that appears as a yellow to orange crystalline powder. It is a key advanced intermediate in the synthesis of afatinib, an EGFR tyrosine kinase inhibitor used for non-small cell lung cancer.
Afatinib intermediate
Category:Organic Intermediates
CAS No.:314771-88-5
Product Grade: Pharmaceutical Grade
Purity / Assay: 98%
Molecular Formula:C₁₈H₁₄ClFN₄O₄
Molecular Weight:404.78
EINECS No.:925-395-5
Synonym(s):(S)-N-(3-Chloro-4-fluorophenyl)-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine
This compound is a quinazoline intermediate that appears as a yellow to orange crystalline powder. It is a key advanced intermediate in the synthesis of afatinib, an EGFR tyrosine kinase inhibitor used for non-small cell lung cancer.
1. Critical intermediate for afatinib API manufacturing.
2. Building block for EGFR inhibitor drug candidates.
3. Precursor for quinazoline-based anticancer agents.
4. Reagent in medicinal chemistry.
25kg/bag; 25kg/drum
CAS No.: 314771-88-5
Product Name: Afatinib intermediate
Purity / Assay:98%
Molecular Formula:C₁₈H₁₄ClFN₄O₄
Molecular Weight:404.78
EINECS No.:925-395-5
Synonym(s):(S)-N-(3-Chloro-4-fluorophenyl)-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine
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