Azilsartan medoxomil (CAS 863031-21-4) is an orally active prodrug that is rapidly converted in vivo to azilsartan, a selective angiotensin II type 1 (AT1) receptor antagonist (IC₅₀ 0.62 nM). It effectively blocks AT1 receptor signaling, thereby interrupting the renin-angiotensin-aldosterone system and modulating vascular resistance. This mechanism makes it a potent antihypertensive agent used in the management of essential hypertension.
Azilsartan medoxomil
Category:Organic Intermediates
CAS No.:863031-21-4
Product Grade: Pharma grade
Purity / Assay: 97%
Molecular Formula:C₃₀H₂₄N₄O₈
Molecular Weight:568.53
Synonym(s):Azilsartan medoxomil; AZM; TAK-491
Azilsartan medoxomil (CAS 863031-21-4) is an orally active prodrug that is rapidly converted in vivo to azilsartan, a selective angiotensin II type 1 (AT1) receptor antagonist (IC₅₀ 0.62 nM). It effectively blocks AT1 receptor signaling, thereby interrupting the renin-angiotensin-aldosterone system and modulating vascular resistance. This mechanism makes it a potent antihypertensive agent used in the management of essential hypertension.
1. API for the treatment of essential hypertension. 2. Prodrug design enables controlled activation in target tissues for improved bioavailability. 3. Used in cardiovascular disease research and pharmacological modulation of blood pressure. 4. Cardiovascular risk management and potential off-label use in post-myocardial infarction or heart failure patients.
25kg/drum; 200kg/drum
CAS No.: 863031-21-4
Product Name: Azilsartan medoxomil
Purity / Assay:97%
Molecular Formula:C₃₀H₂₄N₄O₈
Molecular Weight:568.53
Synonym(s):Azilsartan medoxomil; AZM; TAK-491
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