Candesartan Cilexetil
Candesartan Cilexetil (CAS: 145040-37-5) is a white to off-white crystalline prodrug of candesartan, a selective AT1 angiotensin II receptor antagonist. It is hydrolyzed to the active candesartan during gastrointestinal absorption, providing a long-lasting, dose-dependent reduction in blood pressure for hypertension treatment. The compound is formulated as tablets and is also combined with hydrochlorothiazide for patients needing dual therapy. As a lipophilic ester prodrug, it requires careful control of impurities and degradation products during manufacture and storage. Buyers procure it for the manufacture of branded and generic antihypertensive formulations requiring a stable, well-characterized API.
• Antihypertensive APIs: a prodrug of candesartan used once daily for blood pressure control in adults.
• Combination products: formulated with hydrochlorothiazide for dual-mechanism therapy in single tablets.
• Long duration of action: provides sustained AT1 blockade over 24 hours, improving compliance.
• API manufacturing: supplied for tablet production under pharmaceutical standards with tight impurity control.
Product Name: Candesartan Cilexetil
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