Climbazole
### Climbazole (CAS 38083-17-9): Effective Anti-Dandruff Ingredient for Scalp Care Formulations
Climbazole, identified by **CAS No. 38083-17-9**, is a synthetic imidazole-based antifungal ingredient widely used in cosmetic, personal-care, and scalp-care formulations. It is best known for its anti-dandruff function and is commonly incorporated into rinse-off shampoos, scalp treatments, cleansing products, and specialized hair-care formulas. Climbazole helps inhibit the growth and proliferation of fungi and yeast associated with dandruff-prone scalps, including *Malassezia*. By supporting a healthier scalp environment, it may help reduce the visible appearance of flakes and improve the feeling of scalp cleanliness and comfort.
Climbazole can be combined with soothing, moisturizing, cleansing, and conditioning ingredients to develop advanced anti-dandruff shampoos and scalp-care solutions. Because it has limited water solubility, formulators should carefully evaluate solubilization, dispersion, surfactant compatibility, pH, stability, packaging, microbial protection, and product classification. Usage levels, claims, and permitted applications must comply with the regulations of the target market. In the EU, specific conditions apply to its use in cosmetic products.
**KieRay Chem is a stable and reliable supplier of Climbazole CAS 38083-17-9**, offering consistent quality, dependable supply, professional technical support, and responsive global service. From laboratory samples to bulk procurement, KieRay Chem supports cosmetic manufacturers, shampoo brands, formulators, and distributors worldwide. Choose KieRay Chem for **trusted quality, secure sourcing, reliable delivery, and high-performance anti-dandruff ingredients that help your scalp-care products stand out in competitive global markets**.
**Product: Climbazole (CAS 38083-17-9)**
1. **Anti-Dandruff Function**
Climbazole is a synthetic imidazole-based antifungal ingredient widely used in hair-care and scalp-care products. Its primary cosmetic function is to help control dandruff associated with the excessive growth of fungi, especially *Malassezia*, on the scalp. It is commonly incorporated into rinse-off shampoos, scalp cleansers, and specialized anti-dandruff formulations.
2. **Antifungal and Antimicrobial Activity**
Climbazole works by inhibiting the growth and proliferation of susceptible fungi and yeast. By helping maintain a more balanced scalp microenvironment, it may reduce the visible accumulation of flakes and support a cleaner, healthier-looking scalp. It should not be presented as a cure for a diagnosed fungal infection unless the product is properly authorized as a medicine.
3. **Scalp Comfort and Appearance**
By helping manage microbial imbalance, Climbazole can contribute to reducing the appearance of flaking and the discomfort commonly associated with dandruff-prone scalps. In a well-designed formula, it may support a fresher scalp, improved cleanliness, and better overall hair-care performance. Additional soothing ingredients may be used to enhance comfort.
4. **Preservative Function**
Climbazole is also used as a preservative or antimicrobial protectant in certain cosmetic formulations. It can help inhibit the growth of unwanted microorganisms and therefore support product quality during storage and use. Its preservative role is distinct from its anti-dandruff role, and the permitted concentration may depend on the product type and target market.
5. **Formulation Characteristics**
Climbazole is generally supplied as a white crystalline powder and is poorly soluble in water. It may be incorporated through suitable surfactant systems, solvents, fragrance oils, or other compatible delivery systems. Formulators should evaluate dispersion, pH, temperature, packaging, stability, microbial protection, and compatibility with other active ingredients.
6. **Regulatory and Safety Considerations**
The EU SCCS assessed Climbazole as safe under specified conditions, including up to 0.5% as a preservative in rinse-off shampoo and up to 2.0% as an anti-dandruff agent in rinse-off shampoo. Local regulations may differ, so final concentrations, claims, and product classification must be verified before commercialization.
Product Name: Climbazole
For global customers, we provide complete technical documentation to support product evaluation, regulatory compliance and safe handling during transportation and application.