KIERAY CHEM offers high-purity D-PANTHENOL(CAS 81-13-0), which is suitable for cosmetic-grade applications.
Appearance of D-PANTHENOL sample
D-Panthenol
Category:Cosmetic Ingredients, Daily Chemicals
CAS No.:81-13-0
Product Grade: Cosmetic Grade
Purity / Assay: ≥98%
Molecular Formula:C₉H₁₉NO₄
Molecular Weight:205.25
EINECS No.:201-327-3
Synonym(s):Provitamin B5, Dexpanthenol
D-Panthenol is the provitamin form of pantothenic acid (Vitamin B5) widely used in cosmetic and personal care products. It penetrates the skin and converts to pantothenic acid, providing deep moisturization, soothing and healing benefits. It is essential for maintaining healthy skin and hair barrier function.
Dexpanthenol (CAS 81-13-0) serves as a versatile, biologically active provitamin B5 analog that undergoes enzymatic conversion to pantothenic acid, a crucial constituent of coenzyme A. This biochemical pathway drives cellular metabolism and tissue regeneration across multiple dermatological and pharmaceutical applications:
- Dermatological & Anti-Aging Therapeutics: Penetrates the stratum corneum to optimize epidermal barrier function, enhance transepidermal water loss (TEWL) regulation, and stimulate fibroblast proliferation, effectively mitigating fine lines and restoring elasticity in mature or sensitive skin.
- Wound Healing & Barrier Repair: Accelerates re-epithelialization in minor wounds, burns, and diaper dermatitis by modulating inflammation, facilitating cellular chemotaxis, and establishing a protective lipid barrier to soothe irritated tissue.
- Ophthalmic & Mucosal Management: Included in isotonic nasal sprays and ophthalmic drops to restore mucosal homeostasis, alleviate dryness, and accelerate corneal epithelial healing.
- Trichological Enhancements: Imparts structural integrity to the hair shaft, reinforcing moisture retention within the cortex to minimize cuticle breakage while neutralizing scalp inflammation.
Dexpanthenol (CAS 81-13-0) acts as a highly biocompatible humectant and provitamin B5 analog, optimizing cellular homeostasis and tissue resilience through several mechanisms:
• Transepidermal Barrier Optimization: Formulates deep hydration by attracting moisture while stimulating lipid synthesis to reinforce the epidermal barrier, effectively preventing transepidermal water loss (TEWL) and roughness.
• Anti-Inflammatory & Soothing Efficacy: Demonstrates potent anti-inflammatory properties that mitigate erythema and calm hypersensitive or compromised skin conditions, including eczema, dermatitis, and acute sunburns.
• Accelerated Tissue Regeneration: Drives cellular proliferation and chemotaxis, significantly accelerating re-epithelialization and structural repair in minor wounds, burns, and cutaneous abrasions.
• Trichological & Pediatric Safety: Enhances moisture retention within the hair cortex to minimize shaft breakage, while maintaining an exceptional physiological safety profile ideal for sensitive adult and delicate infant skin.
25kg/drum, 200kg/drum
CAS No.: 81-13-0
Product Name: D-Panthenol
Purity / Assay:≥98%
Molecular Formula:C₉H₁₉NO₄
Molecular Weight:205.25
EINECS No.:201-327-3
Synonym(s):Provitamin B5, Dexpanthenol
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