Diisopropylethylamine
Diisopropylethylamine (CAS: 7087-68-5), widely known as DIPEA or Hunig’s base, is a sterically hindered tertiary amine supplied as a colorless liquid. It is a non-nucleophilic base used extensively in peptide synthesis and pharmaceutical manufacturing to neutralize acids without competing reactions, and it serves as a base and scavenger in alkylation, acylation, and coupling chemistry. Its steric bulk suppresses side reactions that affect less hindered amines. The liquid is easy to meter, recovers by distillation, and stores well sealed. Customers select it where a strong, non-interfering base is required for sensitive synthesis.
• Non-nucleophilic base: a hindered tertiary amine that scavenges acid without side reactions.
• Peptide synthesis: a standard base for coupling, protection, and deprotection steps.
• Pharma manufacturing: supports alkylation, acylation, and coupling chemistry.
• Handling: colorless liquid, easy to meter and recover by distillation.
Product Name: Diisopropylethylamine
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