Ezetimibe
Ezetimibe (CAS: 163222-33-1) is a white to off-white crystalline antihyperlipidemic active ingredient that inhibits intestinal cholesterol absorption. It is used alone or together with statins, alongside diet, to reduce elevated low-density lipoprotein cholesterol in patients with hypercholesterolemia. As a bulk API it is formulated into film-coated tablets for once-daily oral therapy. The compound is practically insoluble in water and is handled as a stable crystalline powder under controlled temperature and humidity. Buyers procure ezetimibe for generic production where compendial quality and consistent lot performance are required.
• Cholesterol API: inhibits intestinal cholesterol and plant sterol absorption at the NPC1L1 transporter.
• Therapy: used alone or with statins to lower LDL-C in hypercholesterolemia.
• Formulation: supplied as a crystalline powder for film-coated tablet manufacture.
• Handling: store under controlled temperature and humidity protected from light and moisture.
Product Name: Ezetimibe
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