Gentamicin sulfate
Gentamicin sulfate (CAS 1405-41-0) is a broad-spectrum aminoglycoside complex derived from the fermentation of Micromonospora purpurea. As a chemical raw material, it typically presents as a white to off-white hygroscopic powder that is highly soluble in aqueous solutions. The substance is a mixture of several related gentamicin components, primarily C1, C1a, and C2, which collectively contribute to its robust biological activity. It is valued for its stability across a wide pH range and its resistance to heat during certain processing stages.
In industrial and research settings, this compound is utilized for its ability to inhibit protein synthesis by binding to the 30S subunit of bacterial ribosomes. Its chemical profile makes it a staple in various laboratory protocols where maintaining a controlled environment is critical. Proper handling requires attention to its hygroscopic nature, necessitating storage in tightly sealed containers to preserve its integrity and prevent degradation over time.
• In the field of biotechnology and cell biology, Gentamicin sulfate is extensively employed as a selective agent in cell culture media. It serves to prevent the growth of various Gram-positive and Gram-negative bacterial contaminants, ensuring the purity of sensitive cell lines during long-term cultivation and expansion processes.
• Within molecular biology research, this compound is utilized as a selection marker for the development of stable cell lines. Researchers leverage its specific inhibitory properties to identify and isolate cells that have successfully incorporated resistance genes, facilitating the study of gene expression and protein function in controlled environments.
• The material is frequently integrated into the formulation of specialized diagnostic reagents and microbiological culture media. Its role here is to suppress the growth of unwanted microflora, thereby allowing for the selective isolation and identification of specific target organisms in complex biological or environmental samples.
Product Name: Gentamicin sulfate
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