Menaquinone-4 (Menatetrenone, MK-4)
Menaquinone-4, commonly identified by the CAS number 11032-49-8 and often referred to as Menatetrenone or MK-4, is a fat-soluble naphthoquinone derivative belonging to the Vitamin K2 family. Characterized by its specific side chain consisting of four isoprene units, this compound appears as a yellow crystalline solid or viscous oil. It is chemically distinct from its counterparts due to its unique metabolic pathways and its role as a primary tissue-specific form of Vitamin K.
In industrial and research settings, MK-4 is valued for its high biological activity and its specific interaction with various protein substrates. Due to its sensitivity to light and oxidative environments, the material requires careful handling and storage, typically under cool, dark conditions to maintain its structural integrity. It serves as a critical raw material in the development of dietary supplements and specialized nutritional formulations aimed at supporting physiological functions.
• In the nutritional and dietary supplement industry, Menaquinone-4 is utilized as a premium fortifying agent. It is incorporated into oil-based softgels, tablets, and functional food products to provide a source of Vitamin K2, which is essential for maintaining calcium homeostasis and supporting skeletal integrity through the activation of specific proteins.
• Within biochemical and pharmacological research, this compound is extensively studied for its role in cellular signaling and gene expression. Researchers utilize MK-4 to investigate its impact on bone mineral density and its potential to modulate inflammatory responses at the molecular level, providing insights into metabolic health and degenerative conditions.
• The material serves as a vital component in the formulation of specialized animal nutrition and veterinary products. It is added to feed premixes to ensure proper bone development and vascular health in livestock and companion animals, particularly in species where endogenous synthesis of Vitamin K may be insufficient.
• In the cosmetic and personal care sector, Menaquinone-4 is occasionally integrated into topical formulations. It is explored for its potential to improve skin appearance and support vascular health within the dermis, often featured in products designed to address dark circles or promote overall skin resilience.
Product Name: Menaquinone-4 (Menatetrenone, MK-4)
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