Methylcobalamin
Methylcobalamin, identified by CAS number 13422-55-4, is a naturally occurring and physiologically active form of Vitamin B12. Chemically, it is a cobalamin featuring a unique cobalt-methyl bond, distinguishing it from other B12 analogs like cyanocobalamin. This deep red, crystalline substance is highly valued in biochemical research and industrial applications due to its role as a critical methyl donor in various enzymatic reactions.
In terms of physical properties, methylcobalamin is notably photolabile, meaning it degrades when exposed to light, requiring careful handling and storage in opaque containers. It exhibits moderate solubility in water and polar solvents. As a key cofactor for the enzyme methionine synthase, it plays a fundamental role in the conversion of homocysteine to methionine, making it an indispensable component in the study of one-carbon metabolism and cellular health.
• In the nutritional and dietary supplement industry, methylcobalamin serves as a premium source of Vitamin B12. It is frequently incorporated into tablets, capsules, and fortified food products due to its high bioavailability and direct participation in metabolic processes without requiring extensive conversion within the body.
• Within the pharmaceutical and clinical research sectors, this compound is utilized as an active pharmaceutical ingredient in formulations targeting neurological health and metabolic pathways. Its involvement in the synthesis of myelin and the maintenance of the nervous system makes it a focal point for studies involving nerve regeneration and cognitive function.
• In biochemical and laboratory settings, methylcobalamin is employed as a reagent to study enzymatic mechanisms and methyl transfer reactions. Researchers utilize it to explore the complexities of the folate cycle and the epigenetic regulation of DNA methylation, providing insights into cellular development and gene expression.
• The material is also applied in the production of specialized animal feed additives. By ensuring adequate B12 levels in livestock and aquaculture, it supports optimal growth rates, efficient feed conversion, and overall metabolic stability in commercial farming environments.
Product Name: Methylcobalamin
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