## Moxidectin (CAS 113507-06-5): Key Functions and Uses
1. **Broad-Spectrum Antiparasitic Agent**
Moxidectin is a macrocyclic lactone anthelmintic used primarily to control susceptible parasitic infections. It belongs to the milbemycin family and is widely recognized for its activity against important nematode and other external or internal parasite species.
2. **Veterinary Parasite Control**
Moxidectin is used in veterinary medicine for livestock and companion-animal parasite management. Depending on the approved formulation and local regulations, it may help control parasites affecting cattle, sheep, horses, dogs, and other animals.
3. **Heartworm Prevention in Dogs**
In approved veterinary products, moxidectin is used to prevent heartworm disease caused by *Dirofilaria immitis*. Certain formulations may also target selected intestinal worms or other susceptible parasites, subject to veterinary direction and product labeling.
4. **Control of Internal and External Parasites**
Moxidectin may be used against susceptible gastrointestinal nematodes, lungworms, mites, and related parasites. Its exact spectrum, dosage, administration route, withdrawal period, and target species depend on the specific veterinary formulation and regulatory approval.
5. **Mechanism of Antiparasitic Action**
Moxidectin acts mainly on parasite ligand-gated ion channels, especially glutamate-gated chloride channels, and may also interact with GABA-related pathways. This disrupts nerve and muscle function, causing paralysis and elimination of susceptible parasites.
6. **Human Medicine for Onchocerciasis**
An approved human pharmaceutical formulation of moxidectin is indicated in some jurisdictions for the treatment of onchocerciasis caused by *Onchocerca volvulus* in eligible patients. Human use must follow an authorized product label and qualified medical supervision; veterinary or research-grade material must never be substituted.
7. **Research and Pharmaceutical Development**
CAS 113507-06-5 is used in veterinary pharmacology, antiparasitic drug research, formulation development, pharmacokinetic studies, resistance monitoring, and analytical testing. It can support investigations into efficacy, safety, metabolism, and parasite susceptibility.
8. **Quality, Regulatory, and Safety Considerations**
When sourcing Moxidectin, buyers should verify identity, purity, formulation, target species, certificate of analysis, storage conditions, residue requirements, and regulatory status. Useful SEO keywords include **Moxidectin, CAS 113507-06-5, macrocyclic lactone, milbemycin anthelmintic, veterinary antiparasitic, heartworm prevention, nematode control, and onchocerciasis treatment**. This compound should be used only according to approved labeling and professional veterinary or medical guidance.
