N-(3-Chloro-4-fluorophenyl)thiourea
N-(3-Chloro-4-fluorophenyl)thiourea is a thiourea derivative carrying chlorine and fluorine on the aromatic ring, supplied as a white to off-white crystalline powder at 98% purity.
The halogen pair tunes both the electron density of the ring and the lipophilicity of the molecule, while the thiourea group provides hydrogen-bond donors and a sulfur chelation site. This profile is widely exploited in medicinal and agrochemical discovery, where thioureas frequently appear as kinase and enzyme inhibitors.
The powder should be stored in a dry, closed container away from strong oxidising agents and acids, and dust generation should be controlled during handling.
• Pharmaceutical intermediates: a building block for aminothiazoles and thiazolines used in drug candidate synthesis.
• Agrochemical synthesis: an intermediate for herbicidal and fungicidal thiourea derivatives.
• Coordination chemistry: forms stable complexes with copper, nickel and palladium for catalysis and analysis.
• Biological screening: used as a thiourea scaffold in enzyme-inhibition and antimicrobial studies.
Product Name: N-(3-Chloro-4-fluorophenyl)thiourea
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