N-(3,4-Dichlorophenyl)thiourea
N-(3,4-Dichlorophenyl)thiourea is a substituted thiourea with two chlorine atoms on the aromatic ring, supplied as a white to off-white crystalline powder at 98% purity.
The thiourea group offers two nucleophilic nitrogen atoms and a sulfur donor, giving the molecule strong chelating and hydrogen-bonding ability, while the dichlorophenyl ring adds lipophilicity and a site for further coupling. This combination supports its role as a building block for heterocycles, as a ligand for metal complexes and as an inhibitor in biological systems.
The powder should be stored in a dry, closed container, away from strong oxidising agents and acids, and handled with appropriate respiratory protection because fine dust can be irritating.
• Heterocycle synthesis: cyclises with haloketones and esters to give aminothiazoles, thiazolines and related heterocycles used as pharmaceutical and agrochemical intermediates.
• Metal-complex ligands: coordinates copper, nickel and palladium for catalytic and analytical applications.
• Enzyme inhibition studies: used as a thiourea-type inhibitor in research on tyrosinase, urease and kinase targets.
• Analytical and coordination chemistry: applied as a reagent for the selective precipitation and spectrophotometric determination of metal ions.
Product Name: N-(3,4-Dichlorophenyl)thiourea
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