N-(Methoxycarbonyl)-L-tert-leucine
N-(Methoxycarbonyl)-L-tert-leucine (CAS: 162537-11-3) is a white crystalline chiral amino acid derivative combining an L-tert-leucine core with a methoxycarbonyl-protected amine. It is a key intermediate for the efficient synthesis of HIV protease inhibitors, most notably atazanavir, where the bulky tert-butyl side chain and protected amine are built into the active structure. The compound also serves as a reference material for atazanavir related-compound analysis. Material is controlled for enantiomeric consistency to support asymmetric API synthesis. Customers procure it for antiretroviral API programs where consistent stereochemical quality is essential.
• Protease inhibitor intermediate: a key chiral building block for atazanavir and related HIV protease inhibitors.
• Protected amine: the methoxycarbonyl group and tert-leucine core are incorporated directly into API structures.
• Impurity reference: serves as atazanavir related compound A for analytical impurity profiling.
• Chiral quality: specified by chemical and enantiomeric purity for asymmetric API synthesis.
Product Name: N-(Methoxycarbonyl)-L-tert-leucine
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