Phenyl Dichlorophosphate
Phenyl Dichlorophosphate (CAS: 770-12-7) is a colorless to pale yellow, moisture-sensitive liquid that functions as a phosphorylating and activating reagent. It is used in organic synthesis to build aryl phosphates, phosphate esters, and phosphoramidates, including intermediates for pharmaceuticals such as antiviral and CNS-active compounds. The compound also serves as a coupling and dehydration agent in specialty chemistry and as a reagent in enzyme-mechanism studies, including work on acetylcholinesterase. It reacts readily with water and alcohols, so dry storage and inert handling are required. Customers value its high reactivity toward nucleophiles and its usefulness in constructing phosphorylated products.
• Phosphorylating agent: installs the phenyl phosphate group onto alcohols and amines to build phosphate esters and amides.
• Pharmaceutical synthesis: used to prepare phosphate ester and phosphoramidate drug intermediates in antiviral and CNS programs.
• Activating agent: promotes condensation and dehydration reactions in fine-chemical synthesis, improving yields.
• Research reagent: employed in studies of acetylcholinesterase decarbamylation and related enzyme chemistry.
Product Name: Phenyl Dichlorophosphate
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