Quinalizarin
Quinalizarin (CAS 81-61-8; 1,2,5,8-tetrahydroxyanthracene-9,10-dione, also called 1,2,5,8-tetrahydroxyanthraquinone) is an anthraquinone compound with formula C14H8O6 and molar mass 272.21 g/mol. Its hydroxylated chromophore gives it color and metal-complexing behavior, supporting niche use in dye chemistry and as an analytical reagent or indicator. It is not highly water-soluble; supplier listings describe dissolution in polar organic solvents such as DMSO or DMF. Confirm grade, assay, and compatibility against the supplier specification for the intended use.
Quinalizarin is also described as a research reagent for biochemical and cell-based studies because it inhibits casein kinase 2 (CK2/CKII); Research descriptions also report its use in cancer-cell mechanism and antimicrobial or antiparasitic assays. These are laboratory research applications, not evidence of an approved medicine, treatment, pesticide, or consumer product. Research and colorant uses should not be presented as established clinical or broadly commercial claims.
– Biochemical research: Quinalizarin is described as an inhibitor of casein kinase 2 (CK2/CKII), with supplier-reported Ki near 0.052 μM. It may be used as a research reagent to investigate CK2-associated phosphorylation and signaling, including reported studies of importin regulation and nuclear transport. This is an experimental tool use, not an approved therapeutic use.
– Cell-biology research: Published supplier descriptions report quinalizarin in studies of cancer-cell responses, including cytotoxicity, oxidative stress, cell-cycle effects, and mitochondrial apoptosis. These are in-vitro or model-system research endpoints; they do not establish clinical efficacy or support claims that the compound treats cancer.
– Specialty color and analytical chemistry: Its anthraquinone chromophore and metal-complexing behavior support niche dye-chemistry and analytical-reagent/indicator applications.
Product Name: Quinalizarin
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