Sacubitril Intermediate
Sacubitril Intermediate (CAS: 752174-62-2) is a chiral amino acid ester that serves as a critical component in the pharmaceutical manufacturing sector. It is most notably recognized as a key precursor in the synthesis of Sacubitril, which is a major constituent of modern cardiovascular medications. The molecule features a biphenyl substituent and specific stereochemistry.
The compound’s defined configuration is vital for ensuring the efficacy of the final therapeutic product. Its high purity and structural integrity are essential for downstream chemical transformations. It is widely used in the production of neprilysin inhibitors, playing a significant role in the development of advanced treatments for heart-related conditions.
– Functions as a primary intermediate in the large-scale industrial manufacturing of the cardiovascular drug Sacubitril. Its specific chiral structure is essential for producing the active pharmaceutical ingredient with the correct stereochemistry required for effective neprilysin inhibition in patients with chronic heart failure conditions.
– Utilized in medicinal chemistry research for the synthesis of various neprilysin inhibitors and related therapeutic agents. Researchers use this intermediate to explore new molecular variations that could lead to improved pharmacological properties or the development of next-generation treatments for cardiovascular and renal diseases.
– Serves as a specialized chiral building block for the construction of complex peptidomimetics in pharmaceutical research. The biphenyl moiety and amino acid ester functionality provide a robust framework for creating diverse molecular scaffolds that mimic natural peptides while offering enhanced stability and biological activity.
– Employed in the development of advanced drug delivery systems and biologically active molecular scaffolds within the pharmaceutical industry. Its well-defined chemical properties make it an ideal starting material for synthesizing complex molecules that require precise spatial arrangements of functional groups for optimal biological interaction.
Product Name: Sacubitril Intermediate
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