Tetra-O-acetyl-beta-D-ribofuranose
Tetra-O-acetyl-beta-D-ribofuranose (CAS: 13035-61-5) is a white to off-white crystalline powder that serves as a protected ribose building block for nucleoside and nucleotide synthesis. The four acetyl groups mask the hydroxyl functions, allowing selective glycosylation at the anomeric position before deprotection under mild conditions. It is a key intermediate in the production of pharmaceutical nucleoside analogues, including antiviral and anticancer active ingredients. The material stores well as a dry solid and is supplied as a free-flowing powder suitable for standard charging and drying operations. Customers select it for nucleoside API programs where consistent quality and reliable lot-to-lot reproducibility are essential for downstream nucleoside manufacture.
• Nucleoside synthesis: a protected ribose donor for building nucleoside analogues used in antiviral and anticancer API programs.
• Pharma intermediate: the tetraacetate pattern enables selective glycosylation chemistry before mild deprotection to the free ribose.
• Process friendly: supplied as a free-flowing crystalline powder that stores well dry and charges cleanly into standard reactors.
• Quality critical: consistent stereochemical purity supports reliable downstream GMP nucleoside manufacture.
Product Name: Tetra-O-acetyl-beta-D-ribofuranose
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