Chemical Products

This compound, diethyl N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamate 4-methylbenzenesulfonate (CAS 165049-28-5), is an advanced protected precursor of the antifolate anticancer drug pemetrexed disodium, sometimes designated pemetrexed intermediate INT-5. It is a solid that must be stored in the dark under inert atmosphere at room temperature because the pyrrolopyrimidinone core is sensitive to light, moisture and oxidation, and it is

4-methylbenzenesulfonate salt of (1R,2S)-2-fluorocyclopropan-1-amine (CAS 143062-84-4), a single-enantiomer fluorinated cyclopropyl amine supplied as a white to off-white crystalline solid with a purity of 98 percent or higher and a reported boiling point near 418 degrees Celsius at 760 mmHg. The molecule pairs a small, strained cyclopropane ring bearing both a fluorine atom and a primary

N-Ethyl-N-methyl)ethanamine(CAS 15180-47-9), also named N-ethyl-N-[(triethoxysilyl)methyl]ethanamine or (diethylaminomethyl)triethoxysilane, is a bifunctional organosilicon reagent that combines a tertiary amine and a triethoxysilane group on the same silicon-carbon tether. It is a colourless to pale yellow liquid with a distinctly amine-like odour, is moisture sensitive and hydrolyses on contact with water or humid air, so it is stored

R salt, or disodium 2-naphthol-3,6-disulfonate (CAS 135-51-3), is a water-soluble naphthalene derivative that carries a phenolic hydroxyl group flanked by two sodium sulfonate groups and is also known as 3-hydroxy-2,7-naphthalenedisulfonic acid disodium salt or R acid disodium salt. The commercial product is usually a pale grey to beige powder with an assay around 85 to

Titanium(IV) sulfate (CAS 13693-11-3) is a white to off-white crystalline titanium salt that dissolves in water with hydrolysis to give strongly acidic solutions of limited stability unless sufficient free acid is present. Solutions tend to precipitate hydrated titania on dilution or heating. As a high-valent and strongly oxophilic metal centre, titanium binds oxygen-donor ligands avidly,

2–1,1-dimethoxyethane (CAS: 1228258-40-9) is a functionalized amino acetal featuring a protected carbonyl group and a primary amine on a compact two-carbon framework. The dimethyl acetal masks an aldehyde functionality that can be revealed under mild acidic conditions, while the free primary amine enables amide formation, reductive amination, and nucleophilic reactions. This dual-reactivity building block is

1,1′-Bi-2-naphthol bis (CAS: 126613-06-7), specifically the bis(triflate) of 1,1′-bi-2-naphthol (BINOL), is a chiral building block derived from enantiomerically pure BINOL featuring triflate leaving groups at the 2,2′-positions. This compound serves as a strategic intermediate for constructing C2-symmetric chiral ligands through palladium-catalyzed cross-coupling reactions replacing triflates with phosphino, amino, or other coordinating groups. The resulting BINAP,

Sodium naphthionate, chemically sodium 4-amino-1-naphthalenesulfonate (CAS 130-13-2), is a crystalline aromatic amine salt manufactured industrially by sulfonating naphthalene and then introducing the amino function. It appears as a pale grey to light pink crystalline powder, typically with an assay of 95 percent or higher based on nitrogen, and dissolves readily in water while remaining only

Androsta-5,16-diene-3beta,17-diol 3-Acetate 17-Triflate (CAS: 115375-60-5) is a steroid intermediate featuring an androstadiene framework with differentiated protecting groups: an acetate at the 3-position and a triflate leaving group at the 17-position. This compound serves as a strategic precursor in the synthesis of abiraterone acetate and related steroidal drugs, where the 17-triflate undergoes palladium-catalyzed coupling with pyridyl

Diethylethoxy)methyl)phosphonate (CAS: 116384-53-3) is an acyclic nucleotide phosphonate intermediate featuring a diethyl phosphonate ester and a purine base connected through an ethoxy linker. This compound serves as a key intermediate in the synthesis of tenofovir and related antiretroviral agents used in HIV and hepatitis B treatment. The phosphonate moiety provides metabolic stability mimicking the natural