1-Chloro-2–4-iodobenzene
1-Chloro-2–4-iodobenzene (CAS: 1103738-29-9) is a dihalogenated aromatic compound featuring both chloro and iodo substituents with differentiated reactivity, enabling selective cross-coupling at the carbon-iodine bond while retaining the chlorine for subsequent transformations. The iodine participates readily in palladium-catalyzed Suzuki, Heck, Sonogashira, and Buchwald-Hartwig reactions under mild conditions, while the chloro group requires harsher conditions, providing orthogonal
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