This compound (CAS 160969-00-6), also named 2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl bromide or 1-(2-bromoethoxy)-2-(2,2,2-trifluoroethoxy)benzene, is a colourless transparent liquid aryl alkyl bromide with a density of about 1.5 grams per cubic centimetre and a purity of 98 percent or higher. As the name implies it contains both a trifluoroethoxy-substituted aromatic ring and a reactive 2-bromoethyl ether chain, and it
This compound, diethyl N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamate 4-methylbenzenesulfonate (CAS 165049-28-5), is an advanced protected precursor of the antifolate anticancer drug pemetrexed disodium, sometimes designated pemetrexed intermediate INT-5. It is a solid that must be stored in the dark under inert atmosphere at room temperature because the pyrrolopyrimidinone core is sensitive to light, moisture and oxidation, and it is
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4-methylbenzenesulfonate salt of (1R,2S)-2-fluorocyclopropan-1-amine (CAS 143062-84-4), a single-enantiomer fluorinated cyclopropyl amine supplied as a white to off-white crystalline solid with a purity of 98 percent or higher and a reported boiling point near 418 degrees Celsius at 760 mmHg. The molecule pairs a small, strained cyclopropane ring bearing both a fluorine atom and a primary
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2-Aminoimidazole hemisulfate (CAS 1450-93-7), also named 2-imidazoleamine sulfate, bis(2-aminoimidazole) sulfate or 2-aminoimidazole sulfate, is the sulfuric acid salt of 2-aminoimidazole, a nitrogen-rich five-membered heterocycle related to the imidazole alkaloids found in marine sponges. It is a white to off-white crystalline solid with a melting point near 270 degrees Celsius, a reported boiling point of about
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Aminoacetonitrile bisulfate (CAS 151-63-3), also described as aminoacetonitrile hydrogen sulfate, sulfuric acid compound with 2-aminoacetonitrile or aminoacetonitrile sulfate, is the sulfuric acid salt of the simplest alpha-aminonitrile. The free nitrile is a low-boiling, strongly basic and hazardous liquid that is awkward to store and dose, so the material is supplied as the stable, water-soluble crystalline
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N-Ethyl-N-methyl)ethanamine(CAS 15180-47-9), also named N-ethyl-N-[(triethoxysilyl)methyl]ethanamine or (diethylaminomethyl)triethoxysilane, is a bifunctional organosilicon reagent that combines a tertiary amine and a triethoxysilane group on the same silicon-carbon tether. It is a colourless to pale yellow liquid with a distinctly amine-like odour, is moisture sensitive and hydrolyses on contact with water or humid air, so it is stored
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Sodium xylenesulfonate (CAS 1300-72-7) is an anionic hydrotrope produced by sulfonating xylene and neutralising the resulting sulfonic acid with sodium hydroxide. It is normally traded as a colourless to pale yellow aqueous solution containing about 40 percent active matter, although a spray-dried solid grade is also available for powder formulations. Unlike a conventional surfactant it
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R salt, or disodium 2-naphthol-3,6-disulfonate (CAS 135-51-3), is a water-soluble naphthalene derivative that carries a phenolic hydroxyl group flanked by two sodium sulfonate groups and is also known as 3-hydroxy-2,7-naphthalenedisulfonic acid disodium salt or R acid disodium salt. The commercial product is usually a pale grey to beige powder with an assay around 85 to
Chloromethyl dimethyl ethoxysilane (CAS 13508-53-7), also written as (chloromethyl)(ethoxy)dimethylsilane, is a bifunctional organosilicon compound that combines a hydrolytically active ethoxy group with a reactive chloromethyl substituent bonded directly to silicon. It is a colourless liquid of moderate volatility that is flammable, corrosive and moisture sensitive, and is therefore stored under an inert atmosphere at two
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Palladium(II) sulfate (CAS 13566-03-5) is an inorganic palladium salt described as a hygroscopic red-brown solid that is normally supplied and handled as the dihydrate and is moderately soluble in water and dilute acid. As a platinum-group metal compound it is expensive and tightly traded, so industrial users recover and recycle palladium from spent solutions rather
Titanium(IV) sulfate (CAS 13693-11-3) is a white to off-white crystalline titanium salt that dissolves in water with hydrolysis to give strongly acidic solutions of limited stability unless sufficient free acid is present. Solutions tend to precipitate hydrated titania on dilution or heating. As a high-valent and strongly oxophilic metal centre, titanium binds oxygen-donor ligands avidly,
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2–1,1-dimethoxyethane (CAS: 1228258-40-9) is a functionalized amino acetal featuring a protected carbonyl group and a primary amine on a compact two-carbon framework. The dimethyl acetal masks an aldehyde functionality that can be revealed under mild acidic conditions, while the free primary amine enables amide formation, reductive amination, and nucleophilic reactions. This dual-reactivity building block is
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Zinc p-toluenesulfonate hydrate (CAS: 123334-05-4) is the zinc salt of p-toluenesulfonic acid providing a source of zinc ions combined with the solubilizing sulfonate anion. This white crystalline compound serves as a catalyst in esterification, polycondensation, and curing reactions where its mild Lewis acidity and solubility in polar media are advantageous. The textile industry employs zinc
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1,1′-Bi-2-naphthol bis (CAS: 126613-06-7), specifically the bis(triflate) of 1,1′-bi-2-naphthol (BINOL), is a chiral building block derived from enantiomerically pure BINOL featuring triflate leaving groups at the 2,2′-positions. This compound serves as a strategic intermediate for constructing C2-symmetric chiral ligands through palladium-catalyzed cross-coupling reactions replacing triflates with phosphino, amino, or other coordinating groups. The resulting BINAP,
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Sodium naphthionate, chemically sodium 4-amino-1-naphthalenesulfonate (CAS 130-13-2), is a crystalline aromatic amine salt manufactured industrially by sulfonating naphthalene and then introducing the amino function. It appears as a pale grey to light pink crystalline powder, typically with an assay of 95 percent or higher based on nitrogen, and dissolves readily in water while remaining only
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Androsta-5,16-diene-3beta,17-diol 3-Acetate 17-Triflate (CAS: 115375-60-5) is a steroid intermediate featuring an androstadiene framework with differentiated protecting groups: an acetate at the 3-position and a triflate leaving group at the 17-position. This compound serves as a strategic precursor in the synthesis of abiraterone acetate and related steroidal drugs, where the 17-triflate undergoes palladium-catalyzed coupling with pyridyl
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